The Mediastinal Mass 2018

Tumors of the mediastinum are usually diagnosed in young patients, but they can develop at any age and form any tissue that exists in or passes through the chest cavity. The diagnosis and the accurate assessment of the mediastinum masses represents a challenge, given their clinical variability from asymptomatic to producing symptoms of cough, chest pain, and dyspnea. Mediastinal tumors encompass a wide range of various neoplasms. The localization of mediastinal masses is critical in the diagnosis: the anterior mediastinal masses are generally thymomas, teratomas, substernal thyroid/parathyroid tissue, or lymphomas; the middle mediastinum massess are typically pericardial and bronchogenic cysts; the posterior mediastinum masses are often neurogenic tumors and esophageal cysts. The wide variety of different entities demonstrates a heterogeneous spectrum of clinical and pathologic features, suggesting that a uniform “standard” management of these patients is not appropriate. In this context, the proposed book will provide a comprehensive review of the mediastinal tumors according to different sites of the diseases, including the masses of anterior, middle and posterior mediastinum. The handling of these tumors requires a multidisciplinary approach due to the complex anatomy of the mediastinum as well as the different clinical, radiographic, and prognostic features. This book has risen from the desire to provide to the specialists in the field an easy, updated and practical guidelines title to facilitate the clinical practice of mediastinic masses. This book will be a comprehensive guide to clinical best practices developed through the opinions of experts in the field.

Table of contents : Front Matter ....Pages i-xii Front Matter ....Pages 1-1 Introduction (Epidemiology, Mediastinal Anatomy, Mediastinal Masses) (Gerardo Botti, Federica Zito Marino)....Pages 3-6 Clinical Approach: Recommendations for the Clinicians (Fortunato Ciardiello, Floriana Morgillo, Giuseppe Viscardi)....Pages 7-15 Mediastinal Masses: Radiological Point of View (Alfonso Reginelli, Anna Russo, Fernando Scala, Elisa Micheletti, Roberta Grassi, Mario Santini et al.)....Pages 17-34 Radiotherapy in Anterior Mediastinum Cancers (Alfonso Reginelli, Anna Russo, Fernando Scala, Elisa Micheletti, Roberta Grassi, Mario Santini et al.)....Pages 35-41 Surgery: Recommendations for Surgeons (Mario Santini, Alfonso Fiorelli)....Pages 43-64 Diagnostic Histopathology Approach (Giulio Rossi, Moira Ragazzi, Alberto Cavazza)....Pages 65-127 Thymic Tumors and Lymphomas: The Clinical Impact of Their Underlying Molecular Features (Francesca Pentimalli, Daniela Barone, Antonio Giordano)....Pages 129-161 Therapy: Recommendations for the Oncologists (Francesco Facchinetti, Letizia Gnetti, Marcello Tiseo)....Pages 163-169 Front Matter ....Pages 171-171 Thymic Neoplasm (Mirella Marino, Francesco Facciolo, Yan Shen, Gabriele Alessandrini, Nicolas Girard)....Pages 173-214 Primitive Mediastinal Germ Cell Tumors: An Update (Andrea Ronchi, Federica Zito Marino, Gaetano Facchini, Marina Accardo, Renato Franco)....Pages 215-227 Thyroid (Maria Grazia Chiofalo, Sergio Venanzio Setola, Fabio Sandomenico, Orlando Catalano, Raffaella D’Anna, Paolo Vallone et al.)....Pages 229-234 Parathyroid (Maria Grazia Chiofalo, Sergio Venanzio Setola, Fabio Sandomenico, Orlando Catalano, Raffaella D’Anna, Paolo Vallone et al.)....Pages 235-239 Mediastinal Lymphoma (Miguel A. Piris, Jorge Muñoz, Socorro M. Rodríguez-Pinilla)....Pages 241-249 Front Matter ....Pages 251-251 Granulomatous Disease (Nicola Martucci, Giuseppe De Luca, Gaetano Rocco)....Pages 253-260 Cysts of the Middle Mediastinum (Giuseppe De Luca, Nicola Martucci, Gaetano Rocco)....Pages 261-269 Tracheal Tumors (Giuseppe De Luca, Nicola Martucci, Gaetano Rocco)....Pages 271-276 Front Matter ....Pages 277-277 Nerve Sheath Tumours, Ganglion Tumours and Neurenteric Cysts (Konstantinos Konstantinidis, Kostas Papagiannopoulos)....Pages 279-288 Esophageal Tumors (Konstantinos Konstantinidis, Kostas Papagiannopoulos)....Pages 289-299 Back Matter ....Pages 301-309

The Mediastinal Mass