Rheumatology, 2-Volume Set, 6e
Stay current in the ever-changing discipline of rheumatology with clear, reliable guidance from Hochberg’s Rheumatology, one of the most respected and trusted sources in the field. Designed to meet the needs of the practicing clinician, this medical reference book provides extensive, authoritativecoverage of rheumatic diseases from basic scientific principles to practical points of clinical management in a lucid, logical, user-friendly manner. "My lasting impression of this book was the very same as the first time I opened these two lavish volumes and that was - wow! This two volume set is a spectacular and seemingly comprehensive review of rheumatology." Reviewed by: Dr Harry Brown Date: Jan 2015 | |||
Table of contents : Content: Front Matter, Pages i-iii Copyright, Page iv Dedication, Page v Contributors, Pages vii-xxii Preface, Page xxiii Acknowledgments, Page xxv 1 - Epidemiologic concepts and classification of rheumatic and musculoskeletal conditions, Pages 1-8 2 - Principles of clinical outcome assessment, Pages 9-19 3 - Principles of health economics and application to rheumatic disorders, Pages 20-26 4 - The synovium, Pages 27-32 5 - Articular cartilage, Pages 33-41 6 - Bone structure and function, Pages 42-55 7 - Tendons and ligaments, Pages 56-60 8 - Connective tissue responses to mechanical stress, Pages 61-64 9 - Biomechanics of peripheral joints, Pages 65-71 10 - Biomechanics of the spine, Pages 72-79 11 - Principles of genetic epidemiology, Pages 80-85 12 - Principles and techniques in molecular biology, Pages 86-98 13 - Cytokines, Pages 99-112 14 - Signal transduction in immune cells, Pages 113-118 15 - Principles of adaptive immunity, Pages 119-126 16 - Principles of innate immunity, Pages 127-133 17 - Systems biology, Pages 134-138 18 - Epigenetics in rheumatology, Pages 139-144 19 - The microbiome in rheumatic diseases, Pages 145-151 20 - Tissue destruction and repair, Pages 152-159 21 - Principles of tissue engineering and cell- and gene-based therapy, Pages 160-164 22 - Osteoimmunology, Pages 165-168 23 - Inflammation and its mediators, Pages 169-182 24 - Scientific basis of pain, Pages 183-187 25 - Effects of the neuroendocrine system on development and function of the immune system, Pages 188-196 26 - Interpreting the medical literature for the rheumatologist: Study design and levels of evidence, Pages 197-203 27 - Ethics in clinical trials, Pages 204-208 28 - History and physical examination, Pages 209-224 29 - Pattern recognition in arthritis, Pages 225-230 30 - Role of laboratory tests in rheumatic disorders, Pages 231-236 31 - Synovial fluid analysis, Pages 237-241 32 - Minimally invasive procedures, Pages 242-249 33 - Skin in rheumatic disease, Pages 250-259 34 - The eye in rheumatic disease, Pages 260-266 35 - The heart in rheumatic disease, Pages 267-273 36 - The lung in rheumatic disease, Pages 274-278 37 - Gastrointestinal tract and rheumatic disease, Pages 279-285 38 - The kidney and rheumatic disease, Pages 286-297 39 - The nervous system in rheumatic disease, Pages 298-305 40 - Conventional radiography and computed tomography, Pages 307-321 41 - Functional magnetic resonance imaging, Pages 322-330 42 - Musculoskeletal ultrasound, Pages 331-341 43 - Bone scintigraphy and positron emission tomography, Pages 342-348 44 - Dual x-ray absorptiometry and measurement of bone, Pages 349-357 45 - Use of imaging as an outcome measure in rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis in clinical trials, Pages 358-368 46 - Arthritis patient education, health promotion, and team approaches to management, Pages 369-374 47 - Principles of rehabilitation: Physical and occupational therapy, Pages 375-381 48A - Complementary and alternative medicine, Pages 382-389 48B - Placebos, caring, and healing in rheumatology, Pages 390-394 49 - Drug development, Pages 395-400 50 - Nonpharmacologic pain management, Pages 401-405 51 - Pharmacogenomics in rheumatology, Pages 406-409 52 - Principles of opioid treatment of chronic musculoskeletal pain, Pages 410-414.e1 53 - Nonsteroidal antiinflammatory drugs, Pages 415-422 54 - Systemic glucocorticoids in rheumatology, Pages 423-433 55 - Nonimmunosuppressive disease-modifying antirheumatic drugs, Pages 434-442 56 - Methotrexate*, Pages 443-450 57 - Leflunomide, Pages 451-458 58 - Immunosuppressives: Cyclosporine, cyclophosphamide, azathioprine, mycophenolate mofetil, Pages 459-467 59 - T-cell costimulation and other directed therapies, Pages 468-471 60 - B-cell depletion, Pages 472-478 61 - Cytokine neutralizers: Interleukin-1 inhibitors, Pages 479-484 62 - Interleukin-6 inhibition, Pages 485-491 63 - Tumor necrosis factor–blocking therapies, Pages 492-510 64 - Kinase inhibition: A new therapeutic principle in rheumatology, Pages 511-517 65 - Emerging therapeutic targets: GM-CSF, IL-17, and IL-23, Pages 518-521 66 - Biosimilars in rheumatology, Pages 522-529 67 - Infections and biologic therapy for rheumatoid arthritis: An update on risk and prevention, Pages 530-535 68 - Drugs and pregnancy, Pages 536-541 69 - Aspiration and injection of joints and periarticular tissue and intralesional therapy, Pages 542-553 70 - Perioperative care of patients with rheumatic disease, Pages 554-565 71 - Neck pain, Pages 567-577 72 - Lumbar spine disorders, Pages 578-594 73 - The shoulder, Pages 595-610 74 - The elbow, Pages 611-618 75 - The wrist and hand, Pages 619-625 76 - The hip, Pages 626-632 77 - The knee, Pages 633-646 78 - The ankle and foot, Pages 647-655 79 - The temporomandibular joint, Pages 656-658 80 - Fibromyalgia and related syndromes, Pages 659-670 81 - Entrapment neuropathies and compartment syndromes, Pages 671-682 82 - Complex regional pain syndrome, Pages 683-689 83 - Classification and epidemiology of rheumatoid arthritis, Pages 691-697 84 - Preclinical features of rheumatoid arthritis, Pages 698-703 85 - Clinical features of rheumatoid arthritis, Pages 704-711 86 - Extraarticular features of rheumatoid arthritis and systemic involvement, Pages 712-719 87 - Adult-onset Still disease, Pages 720-726 88 - Imaging of rheumatoid arthritis, Pages 727-734 89 - The contribution of genetic factors to rheumatoid arthritis, Pages 735-742 90 - Animal models of arthritis, Pages 743-749 91 - Autoantibodies in rheumatoid arthritis, Pages 750-757 92 - Cellular immunity in rheumatoid arthritis, Pages 758-763 93 - Angiogenesis and vasculogenesis in rheumatoid arthritis, Pages 764-767 94 - The rheumatoid joint: Synovitis and tissue destruction, Pages 768-784 95 - Evaluation and management of early inflammatory polyarthritis, Pages 785-789 96 - Evaluation and outcomes of patients with rheumatoid arthritis, Pages 790-801 97 - Management of rheumatoid arthritis: synovitis, Pages 802-808 98 - Multidisciplinary approach to rheumatoid arthritis, Pages 809-814 99A - Evaluation of musculoskeletal complaints in children: Clinical evaluation, Pages 815-819 99B - Evaluation of musculoskeletal complaints in children: Nonautoimmune musculoskeletal disorders, Pages 820-825 100 - Classification and epidemiology of juvenile idiopathic arthritis, Pages 826-832 101 - Clinical features of juvenile idiopathic arthritis, Pages 833-844 102 - Etiology and pathogenesis of juvenile idiopathic arthritis, Pages 845-850 103 - Management of juvenile idiopathic arthritis, Pages 851-861 104 - Juvenile-onset spondyloarthritis, Pages 862-867 105 - Connective tissue diseases in children, Pages 868-875 106 - Rehabilitation and psychosocial issues in juvenile idiopathic arthritis, Pages 876-883 107 - Infectious arthritis I: Bacterial arthritis, Pages 885-893 108 - Infectious arthritis II: Mycobacterial, brucellar, fungal, and parasitic arthritis, Pages 894-904 109 - Lyme disease, Pages 905-911 110 - Rheumatologic aspects of viral infections, Pages 912-917 111 - Acute rheumatic fever, Pages 918-927 112 - Reactive arthritis, Pages 928-940 113 - Classification and epidemiology of spondyloarthritis, Pages 941-945 114 - Clinical features of axial spondyloarthritis, Pages 946-950 115 - Etiology, pathogenesis, and pathophysiology of ankylosing spondylitis, Pages 951-955 116 - Genetics of axial spondyloarthritis, Pages 956-959 117 - Imaging in spondyloarthritis, Pages 960-969 118 - Management of ankylosing spondylitis/axial spondyloarthritis, Pages 970-985 119 - Classification and epidemiology of psoriatic arthritis, Pages 986-988 120 - Clinical features of psoriatic arthritis, Pages 989-997 121 - Etiology and pathogenesis of psoriatic arthritis, Pages 998-1007 122 - Management of psoriatic arthritis, Pages 1008-1013 123 - Enthesopathies, Pages 1014-1020 124 - Epidemiology and classification of systemic lupus erythematosus, Pages 1021-1025 125 - Preclinical features of lupus, Pages 1026-1031 126 - Clinical features of systemic lupus erythematosus, Pages 1032-1044 127 - Genetics of lupus, Pages 1045-1051 128 - Immunopathology of systemic lupus erythematosus, Pages 1052-1067 129 - Animal models of lupus, Pages 1068-1073 130 - Autoantibodies in systemic lupus erythematosus, Pages 1074-1081 131 - Pathogenesis of lupus, Pages 1082-1087 132 - Drug-induced lupus, Pages 1088-1092 133 - Assessing disease activity and outcome in systemic lupus erythematosus, Pages 1093-1098 134 - Management of nonrenal and non–central nervous system lupus, Pages 1099-1106 135 - Treatment of neuropsychiatric lupus, Pages 1107-1111 136 - Systemic lupus erythematosus: Treatment—renal involvement, Pages 1112-1126 137 - Systemic lupus erythematosus in the pregnant patient and neonatal lupus, Pages 1127-1130 138 - Sjögren syndrome, Pages 1131-1143 139 - Antiphospholipid syndrome: Overview of pathogenesis, diagnosis, and management, Pages 1144-1152 140 - Classification and epidemiology of scleroderma, Pages 1153-1158 141 - Assessing disease activity and outcome in systemic sclerosis (scleroderma), Pages 1159-1164 142 - Clinical features of systemic sclerosis, Pages 1165-1176 143 - Etiology and pathogenesis of systemic sclerosis, Pages 1177-1189 144 - Management of systemic sclerosis, Pages 1190-1199 145 - Pulmonary management of systemic sclerosis, Pages 1200-1212 146 - Raynaud phenomenon, Pages 1213-1218 147 - Localized scleroderma and scleroderma-like syndromes, Pages 1219-1223 148 - Clinical features, classification, and epidemiology of inflammatory muscle disease, Pages 1224-1236 149 - Inflammatory muscle disease: etiology and pathogenesis, Pages 1237-1247 150 - Management of inflammatory muscle disease, Pages 1248-1254 151 - Metabolic, drug-induced, and other noninflammatory myopathies, Pages 1255-1263 152 - Overlap syndromes, Pages 1264-1269 153 - Classification and epidemiology of vasculitis, Pages 1271-1279.e1 154 - Biology and immunopathogenesis of vasculitis, Pages 1280-1289 155 - Polyarteritis nodosa and Cogan syndrome, Pages 1290-1299 156 - Polymyalgia rheumatica and giant cell arteritis, Pages 1300-1309 157 - Antineutrophil cytoplasmic antibody–associated vasculitis, Pages 1310-1321 158 - Takayasu arteritis, Pages 1322-1327 159 - Behçet syndrome, Pages 1328-1333 160 - Kawasaki disease, Pages 1334-1337 161 - Henoch-Schönlein purpura/immunoglobulin-A vasculitis, Pages 1338-1343 162 - Cutaneous vasculitis and panniculitis, Pages 1344-1353 163 - Cryoglobulinemia, Pages 1354-1359 164 - Primary angiitis of the central nervous system, Pages 1360-1367 165 - Monogenic autoinflammatory diseases, Pages 1369-1391 166 - Sarcoidosis, Pages 1392-1400 167 - Relapsing polychondritis, Pages 1401-1405 168 - Amyloidosis, Pages 1406-1414 169 - Digital clubbing and hypertrophic osteoarthropathy, Pages 1415-1419 170 - Miscellaneous arthropathies, Pages 1420-1431 171 - Osteoarthritis: Epidemiology and classification, Pages 1433-1440 172 - Local and systemic risk factors for incidence and progression of osteoarthritis, Pages 1441-1446 173 - Clinical features of osteoarthritis, Pages 1447-1453 174 - Animal models of osteoarthritis, Pages 1454-1461 175 - Pathogenesis and pathology of osteoarthritis, Pages 1462-1476 176 - Genetics of osteoarthritis, Pages 1477-1482 177 - Imaging of osteoarthritis, Pages 1483-1491 178 - Assessment of the patient with osteoarthritis and measurement of outcomes, Pages 1492-1497 179 - Preclinical osteoarthritis, Pages 1498-1502 180 - Assessment of imaging outcomes in osteoarthritis, Pages 1503-1507 181 - Management of osteoarthritis, Pages 1508-1514 182 - Diffuse idiopathic skeletal hyperostosis, Pages 1515-1520 183 - Neuropathic arthropathy, Pages 1521-1527 184 - Osteonecrosis, Pages 1528-1535 185 - Rare osteoarthritis: Ochronosis and Kashin-Beck disease, Pages 1536-1547 186 - Epidemiology of gout, Pages 1549-1554 187 - Etiology and pathogenesis of gout, Pages 1555-1568 188 - Clinical gout, Pages 1569-1574 189 - Management of gout and hyperuricemia, Pages 1575-1582 190 - Calcium pyrophosphate crystal–associated arthropathy, Pages 1583-1595 191 - Basic calcium phosphate crystal deposition disease, Pages 1596-1603 192 - Other crystal-related arthropathies, Pages 1604-1608 193 - Rheumatoid manifestations of endocrine and lipid disease, Pages 1609-1614 194 - Hemophilia and von Willebrand disease, Pages 1615-1622 195 - Joint and bone lesions in hemoglobinopathies, Pages 1623-1627 196 - Hemochromatosis, Pages 1628-1632 197 - Epidemiology and classification of osteoporosis, Pages 1633-1640 198 - Clinical features of osteoporosis, Pages 1641-1649 199 - Pathophysiology of osteoporosis, Pages 1650-1655 200 - Biochemical markers in bone disease, Pages 1656-1662 201 - Management of osteoporosis, Pages 1663-1673 202 - Glucocorticoid-induced osteoporosis, Pages 1674-1679 203 - Osteomalacia and rickets, Pages 1680-1687 204 - Primary hyperparathyroidism: Rheumatologic manifestations and bone disease, Pages 1688-1691 205 - Renal osteodystrophy, Pages 1692-1697 206 - Paget disease of bone, Pages 1698-1704 207 - Gaucher disease, Pages 1705-1710 208 - Mucopolysaccharidoses, Pages 1711-1714 209 - Heritable connective tissue disorders, Pages 1715-1723 210 - Hypermobility syndrome, Pages 1724-1727 211 - Skeletal dysplasias, Pages 1728-1733 212 - Bone tumors, Pages 1734-1743 Index, Pages i1-i82 |