GIT

Molecular Pathology of Neoplastic Gastrointestinal Diseases

Molecular Pathology of Neoplastic Gastrointestinal Diseases reviews the molecular aspects that characterize the spectrum of neoplastic conditions that affect the gastrointestinal tract, providing the reader with current up-to-date knowledge. For each disease entity chapters provide reviews on:

the molecular basis of the individual diseasemolecular testing approaches currently available or in development for diagnosis or for gene target characterization for selective targeted therapiesrecommended guidelines for clinical application of molecular tests are included whenever availablemolecular testing for hereditary predisposition or disease riskanimal models and cell culture models of disease

Table of contents :

Front Matter....Pages i-x

Front Matter....Pages 1-1

Mechanisms of Gastrointestinal Carcinogenesis....Pages 3-29

Front Matter....Pages 31-31

Targeted Therapies and Molecular Diagnostics of Gastrointestinal Cancers....Pages 33-41

Molecular Pathology of Barrett’s Metaplasia and Esophageal Adenocarcinoma....Pages 43-52

Molecular Pathology of Squamous Carcinomas of the Esophagus....Pages 53-66

Molecular Mechanisms and Pathology of Gastric Carcinogenesis: Sporadic Cancers....Pages 67-81

Hereditary Diffuse Gastric Cancer and Other Gastric Cancers Associated with Hereditary Predisposition Syndromes....Pages 83-107

Cancer Predisposition Syndromes of the Gastrointestinal Tract....Pages 109-130

Molecular Pathology of Colon and Small Bowel Cancers: Sporadic Type....Pages 131-140