Gastrointestinal Malignancies



This book comprehensively summarizes the current state of knowledge on malignancies of the gastrointestinal tract. Dedicated organ-based chapters evaluate current treatments and management and provide information on incidence, etiology and biological characteristics. The state of the art in the radiologic and endoscopic staging of gastrointestinal malignancies is described, and guidance is offered on the role of interventional radiology and interventional gastroenterology in the treatment of these challenging tumors. In addition, the book explores novel and evolving treatments, including personalized systemic therapy and minimally invasive surgical and radiology techniques, and addresses patient-reported outcomes and survivorship challenges. It closes by discussing animal models of gastrointestinal malignancies and examining the significance of the Ras superfamily of GTPases. It will be of benefit to all surgeons, oncologists and other specialists who treat these malignancies, as well as to trainees looking to increase their understanding of the field.

Table of contents : 
Front Matter....Pages i-vi
Gastric and Small Bowel Tumors....Pages 1-16
Pathologic Features of Esophageal and Gastric Malignancies....Pages 17-43
Pathologic Features of Miscellaneous Foregut Malignancies....Pages 45-58
Management Controversies and Treatment Strategies for Borderline Resectable Pancreatic Cancer....Pages 59-75
Pathologic Features of Primary Pancreatic Malignancies....Pages 77-100
Gall Bladder Cancer....Pages 101-120
Diagnosis and Management of Intrahepatic and Extrahepatic Cholangiocarcinoma....Pages 121-163
Hepatocellular Carcinoma: Surgical Management and Evolving Therapies....Pages 165-183
Clinical Features of Metastatic Hepatic Malignancies....Pages 185-202
Repeat Hepatectomy for Colorectal Liver Metastases....Pages 203-220
Minimally Invasive Surgery of the Liver....Pages 221-231
Locoregional Therapies for Primary and Secondary Hepatic Malignancies....Pages 233-256
Pathologic Features of Primary and Metastatic Hepatic Malignancies....Pages 257-293
Robotic Rectal Cancer Surgery....Pages 295-308
Pathologic Features of Primary Colon, Rectal, and Anal Malignancies....Pages 309-330
Importance of Adequate Lymphadenectomy in Gastrointestinal Cancer....Pages 331-343
Circulating Tumor Cells in Gastrointestinal Cancer: Current Practices and Future Directions....Pages 345-376
Cost-Effectiveness Analysis in Cancer Care....Pages 377-391
Gastrointestinal Malignancy: Genetic Implications to Clinical Applications....Pages 393-479


Gastrointestinal Malignancies