Applied Physiology in Intensive Care Medicine 2: Physiological Reviews and Editorials

The two previous editions of Applied Physiology in Intensive Care Medicine proved extremely successful, and the book has now been revised and split into two volumes to enhance ease of use. In this second volume some of the most renowned experts in the field offer detailed reviews on measurement techniques and physiological processes of crucial importance in intensive care medicine. Throughout, a key aim is to help overcome the fundamental unevenness in clinicians’ understanding of applied physiology, which can lead to suboptimal treatment decisions. Applied Physiology in Intensive Care has been written by some of the most renowned experts in the field and provides an up-to-date compendium of practical bedside knowledge essential to the effective delivery of acute care medicine. It will serve the clinician as an invaluable reference source on key issues regularly confronted in everyday practice.

Table of contents : 

Front Matter....Pages I-XVIII

Front Matter....Pages 1-2

Fluid responsiveness in mechanically ventilated patients: a review of indices used in intensive care....Pages 3-11

Different techniques to measure intra-abdominal pressure (IAP): time for a critical re-appraisal....Pages 13-27

Tissue capnometry: does the answer lie under the tongue?....Pages 29-37

Noninvasive monitoring of peripheral perfusion....Pages 39-49

Ultrasonographic examination of the venae cavae....Pages 51-54

Passive leg raising....Pages 55-59

Sleep in the intensive care unit....Pages 61-70

Magnesium in critical illness: metabolism, assessment, and treatment....Pages 71-83

Pulmonary endothelium in acute lung injury: from basic science to the critically ill....Pages 85-97

Pulmonary and cardiac sequelae of subarachnoid haemorrhage: time for active management?....Pages 99-110

Permissive hypercapnia — role in protective lung ventilatory strategies....Pages 111-120

Acute right ventricular failure—from pathophysiology to new treatments....Pages 121-129

Red blood cell rheology in sepsis....Pages 131-142

Stress-hyperglycemia, insulin and immunomodulation in sepsis....Pages 143-152

Matching total body oxygen consumption and delivery: a crucial objective?....Pages 153-161

Normalizing physiological variables in acute illness: five reasons for caution....Pages 163-171

Interpretation of the echocardiographic pressure gradient across a pulmonary artery band in the setting of a univentricular heart....Pages 173-182

Ventilator-induced diaphragm dysfunction: the clinical relevance of animal models....Pages 183-189

Front Matter....Pages 191-195

Understanding organ dysfunction in hemophagocytic lymphohistiocytosis....Pages 197-206

What is normal intra-abdominal pressure and how is it affected by positioning, body mass and positive end-expiratory pressure?....Pages 1-2

Determinants of regional ventilation and blood flow in the lung....Pages 207-217

The endothelium: physiological functions and role in microcirculatory failure during severe sepsis....Pages 219-226

Vascular hyporesponsiveness to vasopressors in septic shock: from bench to bedside....Pages 227-236

Monitoring the microcirculation in the critically ill patient: current methods and future approaches....Pages 237-249

The role of vasoactive agents in the resuscitation of microvascular perfusion and tissue oxygenation in critically ill patients....Pages 251-261

Interpretation of blood pressure signal: physiological bases, clinical relevance, and objectives during shock states....Pages 263-275

Deadspace ventilation: a waste of breath!....Pages 277-291

Front Matter....Pages 293-301

The role of the right ventricle in determining cardiac output in the critically ill....Pages 303-314

Beyond global oxygen supply-demand relations: in search of measures of dysoxia....Pages 315-316

Breathing as exercise: The cardiovascular response to weaning from mechanical variation....Pages 317-318

Variability of splanchnic blood flow measurements in patients with sepsis – physiology, pathophysiology or measurement errors?....Pages 319-321

Functional hemodynamic monitoring....Pages 323-325

Non-invasive ventilation in acute exacerbations of chronic obstructive pulmonary disease: a new gold standard?....Pages 327-330

The adrenergic coin: perfusion and metabolism....Pages 331-333

Death by parenteral nutrition....Pages 335-338

Ventilator-induced lung injury, cytokines, PEEP, and mortality: implications for practice and for clinical trials....Pages 339-342

Helium in the treatment of respiratory failure: why not a standard?....Pages 343-345

Is parenteral nutrition guilty?....Pages 347-350

Front Matter....Pages 351-353

Using ventilation-induced aortic pressure and flow variation to diagnose preload responsiveness....Pages 355-358

Evaluation of left ventricular performance: an insolvable problem in human beings? The Graal quest....Pages 315-316

Evaluation of fluid responsiveness in ventilated septic patients: back to venous return....Pages 359-361

Mask ventilation and cardiogenic pulmonary edema: “another brick in the wall”....Pages 363-365

Does high tidal volume generate ALI/ARDS in healthy lungs?....Pages 367-369

Weaning failure from cardiovascular origin....Pages 371-373

The hidden pulmonary dysfunction in acute lung injury....Pages 375-377

Can one predict fluid responsiveness in spontaneously breathing patients?....Pages 379-381

The “open lung” compromise....Pages 383-384

Acute respiratory failure: back to the roots!....Pages 385-387

Is right ventricular function the one that matters in ARDS patients? Definitely yes....Pages 389-391

Strong ion gap and outcome after cardiac arrest: another nail in the coffin of traditional acid–base quantification....Pages 393-395

Prone positioning for ARDS: defining the target....Pages 397-399

Back Matter....Pages 401-403

....Pages 405-407

Applied Physiology in Intensive Care Medicine 2: Physiological Reviews and Editorials