Plastic Surgery
Plastic and Reconstructive Surgery: Experimental Models and Research Designs
There is a paradigm shift in plastic and reconstructive surgery from the interest of developing new surgical techniques into the application of new technologies via research based studies on stem cells, tissue engineering and new field of reconstructive transplantation such as e.g. face, hand or larynx transplants. This approach is relatively novel and introduced to plastic surgery within past decade. Thus there is an urgent need to facilitate access to this new knowledge which was not traditionally a part of plastic surgery curriculum. The most efficient way of introducing these new approaches is via presentation of pertinent to different fields (stem cell, transplantation, nerve regeneration, tissue engineering) experimental models which can be used as a tool to develop technologies of interest by different groups of surgeons. These surgical specialities which will be interested and benefit from the book include: plastic and reconstructive surgeons, microsurgeons, hand surgeons, orthopaedic surgeons, neurosurgeons and transplant surgeons.
Table of contents :
Front Matter....Pages i-xviii
Front Matter....Pages 1-1
Microsurgical Techniques in Reconstructive Surgery....Pages 3-10
Arterial and Venous Microanastomosis Models....Pages 11-31
Lymphaticovenous Anastomosis Training Model in Rat....Pages 33-37
Fallopian Tube Anastomosis....Pages 39-43
Vasoepididymostomy Anastomosis....Pages 45-51
The Microsurgical Groin Skin Flap in the Rat Model....Pages 53-62
Free TRAM Flap Model....Pages 63-67
Front Matter....Pages 69-69
Application of Microcirculatory Models in Plastic Surgery Research: Review....Pages 71-82
Standard Cremaster Muscle Model for Ischemia Reperfusion....Pages 83-88
Cremaster Muscle and Effect of Different Anesthetics....Pages 89-96
Microcirculatory Shock Model....Pages 97-102
Radiation and Microcirculation Models....Pages 103-111
Microcirculation and Smoking....Pages 113-118
Microcirculation Model for Invasive Animal Monitoring....Pages 119-126
Cremaster Chamber Model....Pages 127-133
Mouse Cremaster Muscle Allograft Model....Pages 135-138
Microcirculation and Pace Therapy....Pages 139-143
Microcirculation and Hypothermia Model....Pages 145-148
Front Matter....Pages 149-149
Vascularized Composite Allotransplantation Models....Pages 151-159
Rat Hind Limb and Cremaster Allograft Transplantation Model....Pages 161-165
Front Matter....Pages 149-149
Limb and Microcirculation: Cremaster Flap Model....Pages 167-174
Bilateral Vascularized Composite Skin/Bone Transplantation Models....Pages 175-184
Vascular Thymus and Hind Limb Allotransplantation Model....Pages 185-189
Vascular Thymus Transplantation Model....Pages 191-193
Vascularized Skin/Bone Transplantation Model....Pages 195-203
Vascularized Bone-Femur Transplantation Model....Pages 205-211
New Composite Tissue Allograft Model of Vascularized Bone Marrow Transplant: The Iliac Osteomyocutaneous Flap....Pages 213-226
New Modification of the Oldest Flap in Rats to Increase Antigenicity of Transplanted Skin: The Extended Groin Flap Model....Pages 227-236
Combined Semimembranosus Muscle and Epigastric Skin Flap Model....Pages 237-242
Composite Osseomusculocutaneous Thymus Allotransplantation Model....Pages 243-248
Experimental Model for Monitoring of Composite Tissue Transplantation Induced Trauma....Pages 249-253
Cryopreservation in Plastic Surgery: Our Experience and Review of the Literature....Pages 255-264
A Xenotransplantation Model for Vascularized Composite Transplantation....Pages 265-271
Full Face Transplant Model in Rats....Pages 273-281
Hemiface Transplant Model....Pages 283-288
Composite Hemiface/Calvarium Transplantation Model in Rat....Pages 289-293
Maxilla Allograft Transplantation Model in Rat....Pages 295-299
Composite Hemiface/Mandible/Tongue Allotransplantation Model in Rats....Pages 301-310
Composite Osseomusculocutaneous Midface Allotransplantation Model with Motor and Sensory Units....Pages 311-317
Transplantation of the Mystacial Pad....Pages 319-330
Front Matter....Pages 149-149
Heterotopic Transplantation of Total Face/Scalp Flap....Pages 331-340
Non-invasive Monitoring of Skin-Containing Vascularized Composite Allotransplantation....Pages 341-347
Abdominal Wall Transplant Models....Pages 349-360
Penis Allotransplantation Model....Pages 361-368
Composite Orbital and Periorbital Allotransplantation Model....Pages 369-372
Ear Transplantation....Pages 373-376
Heterotopic Vascularized Ovarian Autotransplantation Model in the Sheep....Pages 377-386
Spleen Transplantation Model....Pages 387-397
Vascularized Lymph Node Transplantation Models....Pages 401-404
Front Matter....Pages 399-399
A Contemporary Overview of Peripheral Nerve Research from Cleveland Clinic Microsurgery Laboratory....Pages 405-411
Epineural Sleeve End-to-End Repair....Pages 413-416
Somatosensory Evoked Potential Model for Assessment of Nerve Regeneration....Pages 417-421
Epineural Sleeve Nerve Grafting Technique....Pages 423-435
Single Fascicle Graft Repair Model....Pages 437-443
Nerve Decompression Models in Diabetic Rats....Pages 445-453
Epineural Sheath Grafts for Nerve Regeneration....Pages 455-464
Epineural Tube Repair....Pages 465-476
Tissue Engineered Conduit....Pages 477-484
Venous Conduit as a Model for Nerve Regeneration....Pages 485-491
DRG Decompression Model....Pages 493-497
Front Matter....Pages 399-399
Epineural Patch Applications in Dorsal Root Ganglion Decompression Model....Pages 499-506
Sheep as a Large Animal Model for Nerve Regeneration Studies....Pages 507-511
Peripheral Nerve Surgery Models Sciatic Nerve Crush Injury Model....Pages 513-517
Peripheral Nerve Surgery Models Crush Injury and Epineural Patch....Pages 519-523
Neuroma Model....Pages 525-531
Diabetic Rat Model....Pages 533-540
Nerve Allograft Transplantation Model....Pages 541-547
Nerve Allograft Transplantation....Pages 551-559
Front Matter....Pages 549-549
Application of the Microsurgical Robot RAMS in Plastic and Reconstructive Surgery....Pages 563-567
Front Matter....Pages 561-561
Cellular Therapies in Vascularized Composite Allograft: Review....Pages 569-579
In Vivo Chimera Model: Creation of Primary and Secondary Chimera....Pages 581-591
Cellular Therapy Models: Ex Vivo Chimera Model by Cell Fusion....Pages 593-603
Cellular Therapies via Vascularized Bone Marrow Transplantation....Pages 605-616
Cellular Therapies in Vascularized Composite Allograft....Pages 617-627
Cellular Therapies in Post-radiation Syndrome....Pages 629-636
Cellular Therapies in Nerve Regeneration....Pages 637-644
Back Matter....Pages 645-661
