Thursday, January 12, 2017

Anticoagulation and Hemostasis in Neurosurgery

​This book is an up-to-date reference on all aspects of anticoagulation and hemostasis in neurosurgery. After an opening section on basic principles and drug classes in current use, detailed consideration is given to coagulation issues relevant to all patients, not just neurosurgical ones. The coverage includes, for example, deep vein thrombosis, pulmonary embolism, and disseminated intravascular coagulation. A variety of important issues specific to neurosurgical practice are then addressed, and a summary of current guidelines and best practices is provided. By bringing together the latest knowledge from across the discipline, this book will serve as a sound basis for informed decision making in surgical practice. It will be of daily value for neurosurgeons and trainees worldwide and will also be of interest to emergency room physicians, surgeons in general, critical care physicians, neurologists, and hospital medicine specialists.
Table of contents : 
Front Matter....Pages i-xi
Front Matter....Pages 1-1
Physiology of Hemostasis....Pages 3-16
Laboratory Assessment of Physiologic and Pathologic Hemostasis....Pages 17-31
Current Anticoagulation Drugs and Mechanisms of Action....Pages 33-46
Reversal of Target-Specific Oral Anticoagulants....Pages 47-54
Overview, Measurement and Point-of-Care Testing of Platelet Function....Pages 55-64
Role of Antiplatelet Therapy in Neurosurgery: Efficacy and Safety Profiles....Pages 65-89
Front Matter....Pages 91-91
Congenital Coagulation Disorders....Pages 93-114
Acquired Coagulation Disorders....Pages 115-128
Regulation and Dysregulation of Fibrinolysis....Pages 129-137
Risks Associated with Administration of Allogeneic Blood Components....Pages 139-147
Common Coagulation Disorders That May Arise Intraoperatively: Specifically DIC....Pages 149-152
Evaluation and Management of Untoward Intraoperative Bleeding....Pages 153-165
Treatment of Disseminated Intravascular Coagulation (DIC)....Pages 167-182
Heparin-Induced Thrombocytopenia (HIT)....Pages 183-194
Anticoagulation in Cardiovascular Diseases....Pages 195-214
Workup and Treatment of Pulmonary Embolus....Pages 215-224
Front Matter....Pages 225-225
Classes of Drugs and Blood Products for Acute Reversal of Anticoagulant Effect....Pages 227-242
Rescue Strategies to Facilitate Emergency Neurosurgery in Patients on Antiplatelet or Anticoagulant Agents....Pages 243-256
Considerations for Coagulation in the Multi‐trauma Patient....Pages 257-267
Cerebral Venous Sinus Thrombosis....Pages 269-284
Front Matter....Pages 225-225
Coagulation Studies in Preoperative Neurosurgery Patients....Pages 285-296
Safe Strategies for Gradual Suspension and Reinstitution of Anticoagulation to Permit Elective Surgery....Pages 297-307
Spontaneous Intracerebral Hemorrhage Due to Coagulation Disorders....Pages 309-316
Prophylactic Screening for Venous Thromboembolism in Neurosurgical Patients....Pages 317-325
Venous Thromboembolism Prophylaxis in Neurosurgery....Pages 327-342
Can Patients with Known Intracranial and Intraspinal Vascular Lesions Be Anticoagulated?....Pages 343-361
Intrathecal Access and Devices in Patients on Antiplatelet or Anticoagulant Therapy....Pages 363-368
Is It Safe to Shunt Anticoagulated NPH Patients?....Pages 369-380
Surgical Hemostasis in the Era of Anticoagulation: Guidelines and Recommendations Summary....Pages 381-392
Back Matter....Pages 393-404

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